Alkyl chlorides
Aobchem 1 2 4-Trichloro-3-methylbenzene | ≥97% | CAS 2077-46-5 | C7H5Cl3 | 1g
1 2 4-Trichloro-3-methylbenzene | ≥97% | CAS 2077-46-5 | C7H5Cl3 | 1g
Aobchem 1 2 4-Trichloro-3-methylbenzene | ≥97% | CAS 2077-46-5 | C7H5Cl3 | 500mg
1 2 4-Trichloro-3-methylbenzene | ≥97% | CAS 2077-46-5 | C7H5Cl3 | 500mg
Aobchem 2 3 5-Trichloro-6-methoxypyridine | ≥97% | CAS 31557-34-3 | C6H4Cl3NO | 1g
2 3 5-Trichloro-6-methoxypyridine | ≥97% | CAS 31557-34-3 | C6H4Cl3NO | 1g
Apexbio Technology LLC I-CBP 112 1640282-31-0 5mg
I-CBP 112 (CAS 1640282-31-0) is a selective small-molecule inhibitor targeting the bromodomains of CREBBP (CBP) and EP300 two epigenetic regulators involved in transcriptional control In biochemical assays I-CBP 112 demonstrates an IC50 of 170 nM against CREBBP with marked selectivity over other bromodomain-containing proteins such as ATAD2 BAZ2B and members of the BET family In vitro studies indicate that I-CBP 112 does not exhibit significant cytotoxicity in U2OS cells at concentrations up to 50 M Currently this compound is utilized predominantly in cellular and molecular studies to dissect the function of CREBBP/EP300 bromodomains in gene regulation with ongoing use limited to preclinical in vitro research contexts
Medchemexpress LLC Rapastinel Trifluoroacetate | 1435786-04-1 | 98.0% | 527.49 | 50 MG
Rapastinel Trifluoroacetate | 1435786-04-1 | 98.0% | 527.49 | 50 MG
Medchemexpress LLC Antifungal agent 112 | 68380-53-0 | 99.5% | 287.32 | 25 MG
Antifungal agent 112 (Compound 1e) exhibits antifungal activity against *Candida albicans*, *Aspergillus niger*, and *Aspergillus fumigatus* with MIC values of 0.0024, 0.0022, and 0.0028 M, respectively. It is for research use only and not sold to patients.
- Antifungal activity against *Candida albicans*, *Aspergillus niger*, and *Aspergillus fumigatus*.
- Available in various quantities (5 mg, 10 mg, 25 mg, 50 mg).
- Controlled substance, not for sale in all territories.
Aobchem 2 4 6-Trichloro-3-fluoropyridine | 97% | CAS 52074-47-2 | C5HCl3FN | 1g
2 4 6-Trichloro-3-fluoropyridine | 97% | CAS 52074-47-2 | C5HCl3FN | 1g
Medchemexpress LLC UC-112 | 383392-66-3 | 98.9% | 100 MG
UC-112 is a survivin and XIAP modulator exhibiting anticancer activity. It functions by selectively downregulating and degrading survivin through the ubiquitin-mediated proteasomal pathway. This compound also effectively reduces XIAP levels in in vivo tumor models, leading to the activation of caspase-3/7 and caspase-9, and ultimately inducing apoptosis in cancer cells. It is suitable for research on melanoma, prostate cancer, and other cancer-related studies.
- Selectively downregulates and degrades survivin
- Reduces XIAP levels in in vivo tumor models
- Activates caspase-3/7 and caspase-9
- Induces cancer cell apoptosis
- Inhibits proliferation of A375, M14, PC-3, and DU145 cancer cells
- Alters cell cycle distribution in A375 melanoma cells
- Inhibits human melanoma tumor growth in nude mice
Medchemexpress LLC Spi-112 | 1051387-90-6 | MFCD31620831 | 98.0% | 468.46 g/mol | C22H17FN4O5S | 1 ML
SPI-112 is a potent, selective, and competitive inhibitor of SHP2 (PTPN11) used for in vitro biochemical and biophysical studies. It inhibits SHP2 with an IC50 of approximately 1 μM, with weaker activity against related phosphatases. Kinetic and binding data indicate competitive inhibition (Ki ≈ 0.8 μM) and 1:1 binding by SPR (KD ≈ 1.3 μM). The compound is not cell permeable and is supplied for research applications.
- Inhibits SHP2 with IC50 ≈ 1 μM.
- Shows selectivity over related phosphatases (IC50s 18.3 μM for PTP, 14.5 μM for PTP1B).
- Exhibits competitive inhibition kinetics (Ki ≈ 0.8 μM).
- Binds 1:1 in SPR with KD ≈ 1.3 μM.
- Not cell permeable due to polar or charged functional groups.
- Supplied as a solid and as a 10 mM solution for in vitro assays.
- High purity suitable for biochemical assays (≈98%).
- Store solid at 4°C; in solvent store at -80°C (long term) or -20°C (short term).
eMolecules 38078-09-0 | Diethylaminosulfur trifluoride | Matrix Scientific | MFCD00000363 | 161.190 | C4H10F3NS | 97.000 | CCN(CC)S(F)(F)F | 5g | 389714247
Diethylaminosulfur trifluoride | Matrix Scientific | 38078-09-0 | MFCD00000363 | 161.190 | C4H10F3NS | 97.000 | CCN(CC)S(F)(F)F | 5g | 389714247
eMolecules 1186194-98-8 | 2,4-dichloro-3-(trifluoromethyl)pyridine | Key Organics/BIONET | MFCD12547046 | 215.980 | C6H2Cl2F3N | 97.000 | FC(F)(F)c1c(Cl)ccnc1Cl | 10mg | 564136012
2,4-dichloro-3-(trifluoromethyl)pyridine | Key Organics/BIONET | 1186194-98-8 | MFCD12547046 | 215.980 | C6H2Cl2F3N | 97.000 | FC(F)(F)c1c(Cl)ccnc1Cl | 10mg | 564136012